Amy Schumer's not here for your weight-loss speculations, honey! The comedy queen is setting the record straight, and it's not about fitting into some Hollywood mold.

In a candid Instagram Reel, Schumer revealed the real reason behind her 50-pound weight loss: surviving Cushing syndrome. Not looking hot, people, *surviving*!

Cushing syndrome, for those playing at home, is no joke. The National Institutes of Health describe it as a condition where the body goes wild producing too much cortisol over a long period.

Schumer minced no words, saying she had a disease that made her face super puffy and, you know, could *kill* her.

But thanks to the internet sleuths (and modern medicine!), the disease is now under control. "The internet caught it and the disease has cleared," she quipped.

Now, for those feeling a tad "let down" by her transformation, Schumer has a message: She didn’t lose 30 lbs – it was 50! And she’s not apologizing for it.

The "Trainwreck" star is all about keeping it real. She even admitted to having plastic surgery over the years and using Mounjaro. Transparency is her middle name, apparently.

The best part? She’s pain-free and can finally play tag with her son, Gene. Talk about a win-win!

Always one to engage with her fans, Schumer offered to spill more details about her journey, especially regarding the wild ride that is perimenopause.

But that's not all! Amid swirling divorce rumors with hubby Chris Fischer, Schumer addressed the elephant in the room.

She declared that whatever happens with her marriage has absolutely *nothing* to do with her weight loss or Fischer's autism.

"Fingers crossed," she wrote, adding, "He’s the best." Cryptic, much?

The pair, who tied the knot back in 2018, had tongues wagging last month when whispers of a split surfaced.

Schumer's rep initially shut down the rumors, claiming the "committed" couple was just "privately working through normal issues that couples in long-term marriages have."

But then, dun dun DUN, Schumer posted some ring-less Instagram pics, fanning the flames of speculation even higher.

Fans couldn't help but gush over her slimmer figure, calling her "Benjamin Button" and begging for the secret to her "time machine."

Back in March, Schumer shared her positive experience with Mounjaro, a stark contrast to her "horrible" time with Wegovy years prior. Honesty is the best policy, right?

In fact, Schumer called out celebs in 2023 who were secretly using semaglutide drugs, urging them to come clean.

During an appearance on "Watch What Happens Live With Andy Cohen," she was quoted as saying, "You are on Ozempic or one of those things or you got work done. Be real with the people."

So, there you have it, folks! Amy Schumer is prioritizing her health, being honest about her methods, and navigating the ups and downs of marriage – all while keeping us entertained. What a queen!

One thing's for sure: Amy Schumer isn't afraid to speak her mind, and we're here for it!

And, as always, we'll keep our fingers crossed for Amy and Chris!

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