
Heart disease, a term encompassing a range of conditions affecting the heart, remains a leading cause of mortality worldwide. The statistics are sobering: approximately one in every three deaths globally is attributed to heart disease. This stark reality underscores the urgent need for increased awareness, prevention, and effective treatment strategies.
While some symptoms of heart disease are readily apparent, others can be subtle and easily dismissed. Symptoms like shortness of breath or chest pain are generally recognized, but seemingly unrelated signs like excessive sweating, dizziness, or even swelling in the ankles (sometimes colloquially referred to as "cankles") can also be indicative of underlying heart problems. These vague warning signs highlight the importance of paying close attention to your body and consulting with a healthcare professional if you experience any unusual or persistent symptoms.
Compounding the problem, recent data suggests an alarming increase in the prevalence of several key risk factors associated with heart disease. Since 2020, there has been a notable rise in the number of individuals diagnosed with conditions like heart failure, atrial fibrillation (an irregular heart rhythm), diabetes, and obesity. This convergence of factors creates a perfect storm, further exacerbating the burden of heart disease on individuals and healthcare systems alike.
A recent comprehensive study, known as the Global Burden of Disease study, has shed light on the alarming surge in cases and deaths related to heart disease, also known as cardiovascular disease (CVD). Published in a leading medical journal, the study's findings paint a concerning picture of the current state of cardiovascular health globally.
The study's data reveals a significant increase in the number of deaths attributed to CVD. In 1990, approximately 13.1 million deaths were caused by CVD worldwide. By 2023, this number had skyrocketed to a staggering 19.2 million, marking a dramatic and concerning increase in mortality associated with heart disease.
One particular form of CVD, peripheral arterial disease, affects a significant portion of the population. This condition occurs when fatty deposits accumulate in the arteries, restricting blood flow to the legs. The Global Burden of Disease study estimates that peripheral arterial disease impacts a staggering 122 million people worldwide.
Coronary artery disease, another prevalent form of CVD, also affects a substantial number of individuals. This condition occurs when the heart's blood supply is compromised due to the build-up of fatty substances within the coronary arteries. Worryingly, coronary artery disease affects twice as many people as peripheral arterial disease, impacting an estimated 240 million individuals globally.
It's also important to note that men are statistically more susceptible to death from CVD compared to women, particularly after the age of 50. This disparity highlights the importance of targeted prevention and early detection efforts aimed at men in this age group.
Dr. Harlan Krumholz, a distinguished professor of medicine at the Yale University School of Medicine, emphasized the gravity of the situation. He stated that the Global Burden of Disease study serves as a "wake-up call," highlighting that heart disease remains the world's leading cause of death, with the burden growing fastest in regions with the least resources to combat it.
Dr. Krumholz further emphasized that the knowledge and tools to address the risks associated with heart disease already exist. He believes that if countries take decisive action by implementing effective health policies and strengthening healthcare systems, millions of lives could be saved. This underscores the importance of proactive and preventative measures in combating the global burden of heart disease.
The recent findings of the Global Burden of Disease study echo concerns raised earlier this year by the British Heart Foundation. In May, the BHF issued a warning that deaths from heart disease in the UK had risen for the first time in 50 years, reversing decades of progress.
The BHF's data revealed an alarming 18% increase in heart disease-related deaths among individuals aged 20-64, rising from 18,693 in 2019 to 21,975 in 2023. This increase underscores the growing vulnerability of younger populations to heart disease.
Further data from the BHF reveals that diagnoses of key risk factors for heart disease are also on the rise. Diagnoses of high blood pressure are up by 21%, atrial fibrillation by 10%, and diabetes, a major risk factor for heart disease, by 12%. These trends paint a concerning picture of the increasing prevalence of conditions that contribute to the development of heart disease.
The Global Burden of Disease study identified high blood pressure as the leading cause of CVD, followed closely by unhealthy diets. These findings highlight the critical role of lifestyle factors in preventing and managing heart disease. High blood pressure places undue stress on the cardiovascular system, while unhealthy diets contribute to the build-up of plaque in the arteries.
The study also identified several other contributing factors to CVD, including poor kidney function, lack of exercise, and excessive alcohol consumption. These factors, while potentially modifiable, contribute significantly to the overall risk of developing heart disease.
Notably, the study revealed that obesity and high blood sugar levels are the fastest-growing risk factors for CVD. This alarming trend mirrors the surging rates of obesity and diabetes worldwide, further underscoring the connection between lifestyle choices and cardiovascular health. The rise in obesity and diabetes places an increasing number of individuals at risk of developing heart disease.
This worrying trend comes after decades of progress in reducing deaths from conditions like heart attack and stroke. For years, public health initiatives and advancements in medical treatments have contributed to a steady decline in cardiovascular mortality. However, the recent surge in risk factors and subsequent increase in deaths from heart disease threaten to undo these hard-won gains.
In the UK, the prevalence of obesity and diabetes is particularly concerning. An estimated 29% of the adult population, or 16 million adults, are now classified as obese. Furthermore, 4.6 million people in the UK have diabetes, a condition that significantly increases the risk of heart disease and other health complications.
Fortunately, simple lifestyle changes can significantly reduce your risk of developing heart disease. The National Health Service (NHS) recommends adopting a heart-healthy diet, engaging in regular physical activity, maintaining a healthy weight, quitting smoking, and limiting alcohol consumption.
A heart-healthy diet emphasizes plenty of fresh fruits and vegetables, whole grains, and lean protein sources. Limiting your intake of saturated fats, found in foods like meat pies and butter, is also crucial for maintaining healthy cholesterol levels. Reducing your salt intake to no more than 6 grams per day is also recommended, as excessive sodium contributes to high blood pressure.
Conversely, incorporating foods high in unsaturated fats, such as oily fish (salmon, mackerel), avocados, and nuts and seeds, can benefit your cardiovascular health. Unsaturated fats help to lower bad cholesterol levels and improve overall heart function.

Combining a healthy diet with regular exercise is a powerful strategy for maintaining a healthy weight and reducing your risk of heart disease. Aim for at least 150 minutes of moderate-intensity aerobic exercise or 75 minutes of vigorous-intensity aerobic exercise per week. Regular physical activity helps to strengthen your heart, improve your cholesterol levels, and lower your blood pressure.
Maintaining a healthy Body Mass Index (BMI) is also an important factor in reducing your risk of heart disease and other health problems. Your GP can help you determine your ideal weight and BMI. You can also calculate your BMI online using a variety of free calculators.
Smoking is a major risk factor for atherosclerosis, the hardening of the arteries, which significantly increases the risk of developing heart disease. Quitting smoking is one of the most impactful steps you can take to improve your cardiovascular health. Numerous resources and support systems are available to help you quit smoking successfully.
Excessive alcohol consumption, particularly binge drinking, increases the risk of heart attack. It's essential to adhere to recommended alcohol limits. Men and women shouldn't regularly consume more than 14 units of alcohol per week, spread over at least three days, with several drink-free days each week. Moderation is key to protecting your heart health.
Individuals with diabetes are at a greater risk of developing heart disease. Managing your blood sugar levels through a combination of physical activity, a healthy diet, and, if necessary, medication, is crucial for protecting your cardiovascular health. Regular monitoring of your blood sugar levels is also essential for effective diabetes management.
Regularly monitoring your blood pressure, cholesterol levels, and blood sugar levels is crucial for early detection and management of risk factors for heart disease. These tests can identify potential problems before they develop into more serious conditions. Consult your GP to determine an appropriate screening schedule based on your individual risk factors.
If you have been diagnosed with heart disease and prescribed medication, it is imperative to take your medication as directed and follow the correct dosage. Do not discontinue or alter your medication regimen without first consulting your doctor, as this can have serious consequences for your health.
It's estimated that approximately 7.6 million people in the UK are currently living with heart disease, and this number is projected to rise by 2 million by 2040. This underscores the growing burden of heart disease on the UK healthcare system and the need for increased preventative measures.
Heart and circulatory diseases account for approximately a quarter (26%) of all deaths in the UK, resulting in more than 170,000 deaths each year. These statistics highlight the significant impact of heart disease on mortality rates in the UK.
There are four primary types of heart disease: coronary heart disease, stroke, peripheral arterial disease, and aortic disease. Understanding the differences between these conditions is crucial for effective diagnosis and treatment.
Coronary heart disease involves the blockage or reduction of blood supply to the heart, typically caused by the build-up of fatty substances in the arteries. This can lead to angina (chest pain), heart attacks, or heart failure.
Strokes occur when the oxygen supply to the brain is interrupted, often due to blood clots. Strokes can cause significant disability and even death. Prompt medical attention is crucial for minimizing the damage caused by a stroke.
Peripheral arterial disease is characterized by a blockage in the arteries supplying blood to the limbs, usually the legs. This can cause pain or weakness, particularly during exercise, and in severe cases, can lead to amputation.
Aortic disease involves the weakening and bulging of the wall of the aorta, the largest blood vessel in the body that carries blood from the heart to the rest of the body. This can cause pain in the chest, back, or abdomen and can be life-threatening if the aorta ruptures.
Despite being a leading cause of death in the UK, the symptoms of heart disease can be subtle and often go unnoticed. Symptoms may not always involve the chest and can manifest in various parts of the body. This highlights the importance of being aware of potential warning signs and seeking medical attention when appropriate.
Professor Elijah Behr, a consultant cardiologist at Mayo Clinic and St George's, emphasizes the importance of recognizing "serious red flags" associated with heart disease. He notes that some individuals may have risk factors for heart disease without experiencing any obvious symptoms.
Professor Behr highlights the importance of recognizing symptoms associated with coronary artery disease, a common cause of heart disease. He emphasizes that while some individuals may not experience obvious symptoms, certain warning signs should raise concern.
Panting or wheezing can be indicative of underlying heart problems. Feeling short of breath may suggest heart failure, often caused by coronary heart disease, an abnormal heart rhythm, or even an impending heart attack.
Breathlessness on exertion, even during mild activity, can be a sign of coronary artery disease. This symptom occurs when the heart is unable to pump enough oxygen-rich blood to meet the demands of the body.
Professor Behr elaborates on the symptoms of heart failure, noting that they can include breathlessness on exertion and, in severe cases, breathlessness even at rest. He explains that some individuals may experience breathlessness when lying flat in bed and may require pillows to elevate their upper body.
Swelling in the ankles can also be a sign of heart failure, as well as poor circulation in the legs. This symptom can indicate a clot in the leg, obstructing blood flow back to the heart. It's important to note that swelling can also be caused by other conditions, but it should always be evaluated by a healthcare professional.

Professor Behr explains that swelling in the ankles or abdomen can be potential signs of developing heart failure. This occurs due to fluid retention caused by the heart's inability to pump blood effectively.
Palpitations, or the sensation of your heart fluttering, can also be a sign of heart disease, specifically an arrhythmia, which is a disturbance in the heart's rhythm. The heart rhythm may be racing, erratic, or both.
Lightheadedness and dizzy spells can occur when the heart isn't pumping enough blood to the brain. This can be a result of heart failure, an arrhythmia, or other underlying heart conditions. It's important to consult a healthcare professional to determine the cause of these symptoms.
Professor Behr emphasizes that severe rhythm disturbances can cause dizziness or loss of consciousness. He advises that abrupt loss of consciousness and palpitations causing dizziness should be considered serious red flags and warrant immediate medical attention.
Poor circulation can cause parts of your skin, particularly your fingers and toes, to turn blue or grey. This indicates narrowed or blocked blood vessels, restricting blood flow to those areas.
Professor Behr explains that skin discoloration can be associated with diseases affecting the blood vessels supplying the skin, potentially indicating coronary artery disease. The appearance of the skin can provide valuable clues about underlying cardiovascular health.
Professor Behr further explains that congestion of tissues due to blood and fluid backup in the heart and body can occur in heart failure. This congestion can lead to swelling and affect the skin's color and texture, typically at a later stage of heart failure.
Men experiencing difficulties with sexual performance may also be at risk of heart disease. Problems achieving an erection can indicate a compromised blood supply to the penis, suggesting potential issues with the arteries. Erectile dysfunction is often a sign of underlying cardiovascular problems.
Professor Behr notes that erectile dysfunction is quite common and can be a sign of problems in the arteries supplying that part of the anatomy. He emphasizes that it can also be associated with conditions like high blood pressure and high cholesterol, making it an advanced sign of potential cardiovascular issues.
Heart failure can cause excessive fatigue as the organ struggles to pump enough blood throughout the body. This can lead to a general feeling of tiredness and lack of energy, impacting daily activities.
Professor Behr emphasizes that fatigue is more likely associated with heart failure symptoms. Persistent and unexplained fatigue should be evaluated by a healthcare professional, particularly if accompanied by other potential symptoms of heart disease.
Sleep apnea, a condition where breathing stops and starts during sleep, can increase the risk of high blood pressure, abnormal heart rhythms, strokes, and heart failure. Untreated sleep apnea places significant stress on the cardiovascular system.
Snoring, particularly when interrupted by pauses in breathing, can reduce the amount of oxygen reaching the brain. This prompts the brain to signal the heart to work harder to circulate blood, increasing the risk of cardiovascular complications. Addressing sleep apnea can significantly improve cardiovascular health.
While feeling hot and clammy on a warm day is usually harmless, excessive sweating accompanied by other symptoms like chest pain radiating down the arms or back, shortness of breath, dizziness, nausea, and fatigue can indicate a heart attack.
Sweating can also be associated with atherosclerosis, a condition where arteries narrow due to the buildup of fatty deposits. Atherosclerosis can lead to heart attack and heart failure as it forces the body to work harder to deliver blood to vital organs, including the heart.
Angina, or chest pain, occurs when the heart doesn't receive enough oxygen-rich blood. Individuals experiencing angina often break out in a cold sweat. It's essential to seek medical attention if you experience angina, particularly if it is new or worsening.
A gripping, cramping sensation in your calves while walking can be a symptom of peripheral arterial disease (PAD). This indicates a build-up of fatty deposits restricting blood supply to leg muscles. Prompt diagnosis and treatment can help prevent further complications of PAD.
While occasional nausea is common and not always indicative of heart problems, experiencing nausea alongside chest pain is a cause for concern. This combination of symptoms may indicate a heart attack and requires immediate medical attention.
Professor David Newby, a cardiologist at the BHF Centre of Research Excellence at the University of Edinburgh, advises that experiencing intense chest pain even when at rest, coupled with nausea, warrants calling an ambulance immediately. Time is of the essence when dealing with a potential heart attack.
If experiencing discomfort in your chest accompanied by nausea, contact 111 for advice. While not always indicative of a heart attack, these symptoms should be evaluated by a healthcare professional to rule out any potential cardiovascular issues.
During a heart attack, pain may radiate beyond the chest to other areas of the body, including the arm, jaw, neck, or back. This radiating pain can be a key indicator of a heart attack and should prompt immediate medical attention.
Pain radiating down the arm, particularly the left arm, or into the neck is more likely to indicate a heart attack. These specific patterns of pain are important warning signs that should not be ignored.